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Original Article
Immunologic Abnormalitiesin Kawasaki Diseaseand the Effect ofIntravenousImmunoglobulin
Joon Sung Lee, Bin Cho, Sung Hoon Cho
Clin Exp Pediatr. 1996;39(5):691-702.   Published online May 15, 1996
Purpose : It has been suggested that immunologic abnormalities play a role in the pathogenesis of vascular injury in Kawasaki disease and the immunologic abnormalities could be regulated by high-dose intravenous immunoglobulin(IVIG). We investigated the peripheral blood lymphocyte subsets, the serum levels of interleukin-6(IL-6) and tumor necrosis factor-α(TNF-α) and the effect of high-dose IVIG(400 mg/kg/day for 5 days) on these factors during acute stage of...
Chronic Cough in Children
Bin Cho, Joon Sung Lee, Kyung Tai Whang, Sung Hoon Cho
Clin Exp Pediatr. 1994;37(8):1116-1123.   Published online August 15, 1994
Chromic cough is a symptom frequently encountered by the pediatrician. Although most coughs are self-limited, chronic cough ofter proves to be a frustrating problem. This study was performed at Kangnam St. Mary's Hospital from January 1,1992 to December 31, 1992, and 83 children with chronic cough persisting for longer than 3 weeks was evaluated. We categorized these patients into 5...
The Factors on the Development of Coronary Arterial Involvement in Kawasaki Disease
Sang Yen Kim, Jong Hyun Kim, Jong In Byun, Won Bae Lee, Byung Churl Lee, Kyung Tai Whang, Kyong Su Lee, Sung Hoon Cho
Clin Exp Pediatr. 1992;35(10):1328-1335.   Published online October 15, 1992
In Kawasaki disease, coronary arterial involvement is an important prognostic factor. Many studies have reported about risk factors of coronary artery disease in Kawasaki disease. This study was designed to evaluate factors influencing coronary arterial involvement and to evaluate the effect of intravenous gammaglobulin (IVG) when admitted on the widely used criteria in Korea. Fiftyfour patients meeting the CDC criteria...
Case Report
A Case of Unilateral Absence of Pulmonary Artery
Joon Ho Bang, Sang Nyen Kim, Jong In Byun, Won Bae Lee, Byung Churl Lee, Kyong Su Lee, Sung Hoon Cho
Clin Exp Pediatr. 1992;35(6):873-878.   Published online June 15, 1992
A Unilateral Absence of Pulmonary Artery(UAPA), which develops occasionally as one of the associated anomaly in congenital cardiovascular defect like as tetralogy of Fallot, is rare anomaly as an isolated congenital defect. We have recently experienced a case of UAPA in a 9 years old boy, which was diagnosed by perfusion scan, digital subtraction angiography. So we report this case...
A Case of Broad QRS Paroxysmal Supraventricular Tachycardia That is Difficult to Differentiate from Ventricular Tachycardia
Hung Ki Min, Hyun Hi Kim, Jong Wan Kim, Kyung Tai Whang, Sung Hoon Cho
Clin Exp Pediatr. 1992;35(2):257-262.   Published online February 15, 1992
A narrow QRS paroxysmal supraventricular tachycardia is a common dysrrhythmia and medical emergency in childhood. We experienced a case of broad QRS type paroxysmal supraventricular tachycardia which was induced by transesophageal pacing technique and the morphology of the QRS complex was similar to that of ventricular tachycardia. So, We report this with a brief review and its related literatures.
Original Article
Molecular analysis of childhood acute lekemia.
Hack Ki Kim, Kyong Su Lee, Sung Hoon Cho, Du Bong Lee
Clin Exp Pediatr. 1991;34(2):164-171.   Published online February 28, 1991
Immunoglobulin (Ig) and T cell receptor 0 chain (TcR分) gene rearrangements can be used as ”genetic marker” of lineage and clonality in the study of lymphoproliferative disease. We analyzed genomic DNA of the bone marrow mononuclear cells from twenty six patients with acute leukemia in children. The patients were seventeen cases of acute lymphocytic leukmia (ALL), seven cases of acute nonlymphocytic leukemia (ANL) and...
Immunologic Changes in Bronchial Asthma on Immunotherapy.
Joon Sung Lee, Kyung Tai Whang, Sung Hoon Cho
Clin Exp Pediatr. 1990;33(9):1255-1261.   Published online September 30, 1990
The best treatment of allergic disease is to avoid exposure to known allergen. Immunotherapy has been attempted in IgE-mediated allergic patients who didn’t show any responses to pharmacologic therapy or couldn’t avoid allergen. There have been many enthusiastic claims for symptomatic relief of allergic disease by various forms of hyposensitization, first introduced by Noon and Freeman (1911) in the treatment of hay fever. The mechanism of...
A case of bronchopulmonary dysplasia.
Sun A Chun, Byung Jun Choi, Bo Kyung Cho, Chung Sik Chun, Sung Hoon Cho
Clin Exp Pediatr. 1989;32(11):1553-1559.   Published online November 30, 1989
The development of respiratory management of the newborn has improved the survival rates of respiratory distress syndrome in these two decades. But the incidence of complication associated with this management has been increased. Although the pathogenesis of bronchopulmonary dysplasia has not been clearly established yet, bronchopulmonary dysplasia is one of the major complication of the mechanical ventilation. There are several factors in the development of...
Clinical Analysis of Congenital Malformations in the Newborn Infant.
Hoon Chang, Chae Hwa Lee, In Kyung Sung, Byung Churl Lee, Sung Hoon Cho
Clin Exp Pediatr. 1988;31(1):72-77.   Published online January 31, 1988
Congenital malformations are still one of the leading problems of neonatal death and illness. But, we have only a few data for about it, because of difficulty in the exact analysis of the incidence and etiologic factors. During the period of 6 years, between January 1980 and December 1985, a clinical study about the general incidence of congenital malformations was done on 50, 979...
Clinical Study of Congenital Hypothyroidism.
Byung Churl Lee, Soon Joo Lee, Sung Hoon Cho
Clin Exp Pediatr. 1987;30(12):1401-1408.   Published online December 31, 1987
We reviewed 24 patients with congenital hypothyroidism to observe the etiology, clinical symptoms and signs, bone age, height age, the degree of mental retardation and growth velocity after treatment form Jan. 1983 to June 1987. The results were as follows: 1) The male to female ratio was about 1:3.8. The cases diagnosed under 1 year old were only 12.5%. 2) In etiologic classification, thyroid dysgenesis...
Statistical Observations for Pediatric Inpatients.
Byung Cheol Han, Hack Ki Kim, Byung Churl Lee, Kyong Su Lee, Sung Hoon Cho, Du Bong Lee
Clin Exp Pediatr. 1987;30(4):385-392.   Published online April 30, 1987
We observed the patients admitted to the department of pediatrics of St. Mary*s Hospital, Catholic Medical College during the past 20 years from Jan. 1966 to Dec. 1985 and classified them by year and disease according to the International Classification of Disease by W.H.O. (1965 Revision). The results were as follows: 1) The total number of pediatric inpatients during 20 years was 18,686, of which...
Case Report
A Case of Neurofibromatosis.
In Kyung Sung, Sung Won Kang, Ik Jun Lee, Sung Hoon Cho
Clin Exp Pediatr. 1983;26(1):97-101.   Published online January 31, 1983
Neurofibromatosis, first described by Von Recklinghausen in 1882, is characterized by multiple areas of pigmentation in association with tissue overgrowth of nerve sheath and fibrous tissue elements. We experienced a case of neurofibromatosis with megalencephaly in a 12-years old boy. A brief review of the related literature is given.
A Case of Moyamoya Disease with Focal Seizure.
Man Gee Hong, Hak Ki Kim, Kyung Tai Whang, Sung Hoon Cho
Clin Exp Pediatr. 1982;25(10):1053-1057.   Published online October 31, 1982
We experienced a case of Moyamoya syndrome in a 4 year-old girl. The patient was well until 3 years of age when she first experienced numbness of the left arm. After 10 days of above episode, she had tonic-clonic movements of left sided extremities which lasted, approximately 2 hours and followed by paresis. During the following week the second attack of focal seizure followed...
Original Article
A Case of Infantile Cortical Hyperostosis.
Won Bae Lee, Hyun Koo Oh, Jae Chung Lee, Sung Hoon Cho
Clin Exp Pediatr. 1982;25(8):839-842.   Published online August 31, 1982
Infantile cortical hyperostosis occurs in the first few months of life, and is characterized by irritability, fever, soft tissue swelling and radiological evidence of a periosteal reaction, particularly of the mandible. It's cause is unknown. The disease has been reported over 130 cases worldwidely, with only 2 cases in Korea sofar. Recently we experienced a case of infantile cortical hyperostosis....
Epidemiological Study on Diseases of Korean Children in Urban & Rural Areas.
Du Bong Lee, Sung Hoon Cho, Kyong Su Lee, Byung Churl Lee
Clin Exp Pediatr. 1980;23(3):173-197.   Published online March 15, 1980
This study was attempted to know the recent changes of the patterns of diseases among Korean children living inurban and rural areas. 21,498 sick-children, who admitted to the thirteen general hospitals which located in urban and rural areas during past five years from Jan. 1994 to Dec. 1978, were analysed for this purpose. 13,759 sick-children(64.0%) were male, others were female...
A Clinicoelectroencephalographic Study of Febrile Convulsion and Epilepsy in Childhood.
Kyung Tai Whang, Sung Hoon Cho
Clin Exp Pediatr. 1979;22(2):131-140.   Published online February 15, 1979
This study was attempted to reveal the clinical and electroencephalographic findings in children who were experienced febrile convulsion and epilepsy. The subjects were 226 cases, under 15 years of age, who visited with convulsive disorders to the St. Mary's hospital between Jan. 1977 and Aug. 1978. Of these, 45 cases were febrile convulsion and 123 cases were epilepsies. The results...
Case Report
A Case of Takayasu's Arteritis with Congestive Heart Failure.
Yo Joong Kim, Sang Min Seong, Kyung Tai Whang, Sung Hoon Cho, Kyung Sub Shinn
Clin Exp Pediatr. 1978;21(10):682-684.   Published online October 31, 1978
A 38 month old girl was admitted with the episode of anorexia, coughing and dyspnea to St. Mary's hospital on Nov. 9, 1977. She had treated as hepatitis at private clinic for one month before admission, however these symptoms were aggrevated with coughing and progressed dyspnea since a week ago. On physical examination, body temperature 36.8C, body weight 11.7kg, heart...
A Case of Hepatoblastoma.
Young Hun Kwack, Sung Chul Son, Kyung Tai Whang, Sung Hoon Cho, An Hi Lee, Chong Moo Lee
Clin Exp Pediatr. 1978;21(4):299-304.   Published online April 30, 1978
We have experienced a case of hepatoblastoma in 22 months old male infant who presented with abdominal distention and hepatomegaly. Diagnosis was confirmed by X-ray of abdomen, liver scan and histological findings. A brief review of literature was also presented.
Original Article
Clinical Evaluation of Children with Psychiatric Problems among Pediatric Patients.
Kyung Tai Whang, Byung Churl Lee, Sung Hoon Cho, Haeng Sook Kim
Clin Exp Pediatr. 1978;21(3):198-206.   Published online March 31, 1978
Patients who visited to the pediatric department sometimes present psychiatric problems, but this interesting field seems to have been neglected frequently by clinicians. The authors were analyzed 130 cases of pediatric patients who referred to psychiatric department for the evaluation of psychiatric problems from July, 1974 to June, 1977 at the St. Mary's hospital, Catholic medical college. The results were...
Case Report
A Case of Cornelia de Lange Syndrome
SooWung Lee, Moo Kil Park, Choo Hyun Kim, Sang Duk Cha, Churl Young Chung, Sung Hoon Cho, Jung Ja Kim, Yong Whee Park, Chin Hee Cho, Byoung Kie Kim
Clin Exp Pediatr. 1974;17(4):312-320.   Published online April 30, 1974
We have experienced a case of Cornelia de Lange syndrome in 21 day old female. She showed typical clinical features of a microbrachycephaly, hirsutism and characteristic face- with low forehead bushy eyebrows, antimongolian slant, large and depressed bridge of nose, thin protruding lips with downturning of the corners and micrognathia. She had also skeletal, dermatoglyphic and chromosomal abnormalities. The diagnosis was established by clinical,...
Original Article
Clinical Observation of Intussusception in Infancy and Childhood
III Woong Lee, Suck Hi Kim, Sung Hoon Cho
Clin Exp Pediatr. 1973;16(11):844-853.   Published online November 30, 1973
Intussusception is the one of frequent and emergency surgical conditions in infancy and childhood. The clinical study of 106 cases of intussuscepton, who were admitted at the St. Mary’s Hospital during the past five years from January 1967 to December 1972, was reviewed. The results of this study were as follows; 1)In age incidence, 68. 9% of the patients were...
Case Report
Muco-Cutaneous Lymphnode Syndrome(Five Cases Report)
Chung Sook Park, Choon Ji Suh, Sung Hoon Cho, Du Bong Lee
Clin Exp Pediatr. 1973;16(7):565-571.   Published online July 31, 1973
So-called Muco-Cutaneous Lymphnode Syndrome (MCLS) was reported first in 1967 by Tomisaku Kawasaki Department of Pediatrics, Japanese .Red Cross Central Hospital, Tokyo, Japan and then over 1,857 cases of this syndrome has been reported in Japan recently until 1971. This syndrome was characterized by the continued high fever durated over 10 days. The swelling of cervical lymphnodes simulating Mumps, generalized...
Original Article
Statistical Observation of Hemolytic Streptococcal Infections
Bang Sup Lee, Young Koo Yeo, Hong Yul Lee, Sung Hoon Cho
Clin Exp Pediatr. 1973;16(6):479-485.   Published online June 30, 1973
Auther observed statistically 302 cases of hemolytic streptococcal infections in Korean children who had admitted to Dept, of Ped., St. Mary’s Hospital from Jan. 1966 to June 1972. The results were as follows: 1)The incidence of streptococcal infections in 4,739 hospitalized sick children was 6.3%. Among 302 cases, 176 cases (59.2%) were female. The annual incidence was highest in 1966 (8.9%)....
Clinical Observation for Hematologic Disorders in Children
Bang Sup Lee, Yong Kuk Kim, Sang Duk Cha, Sung Hoon Cho
Clin Exp Pediatr. 1972;15(9):797-805.   Published online September 30, 1972
170 cases of hematologic disorders in children who were admitted to Dept, of Ped., St. Mary’s Hospital from Jan. 1963 to Aug. 1971 were analysed clinically. The 170 included 118 males and 52 females. The results were as follows: 1. The age incidence of leukemia, idiopathic thrombocytopenic purpura (I.T.P.), anaphylactoid purpura and iron deficiency anemia were 3〜5 years, under 5 years, 3〜9 years and under...
Case Report
A cases of Hydrometrocolpos associated with Congenital Anormalies of the Intestine
Dong Soo Kil, Whan Kim, Sung Hoon Cho
Clin Exp Pediatr. 1972;15(2):156-160.   Published online February 28, 1972
A cases hydrometrocolpos associated with an imperforated anus, malrotation of the intestine and small' bowel obstruction due io annular fibrotic band in a newborn is presented. The patient had complaints of dyspnea, marked abdominal distention, edema around vaginal outlet and both legs. The diagnosis was confirmed by physical findings, vaginogram and exploratory laparatomy. The review of literature was made briefly.
A Case Report of Congenital Adrenogenital Syndrome
Chung Kyu Kim, Kwang Ho Pyun, Kyung Tai Whang, Sung Hoon Cho
Clin Exp Pediatr. 1971;14(5):313-318.   Published online May 31, 1971
This is a case report of the hypertensive form of adrenogenital syndrome. The patient was a 3 years old boy who entered at Department of Pediatrics, St. Mary’s hospital on July 1, 1969 with the episodes of accelerated growth, enlargement of penis' and appearence of pubic hair. At birth, the patient showed no obvious abnormalitier in external genitalia. His height...
Original Article
Clinical observation of five cases of thyroid disease in Childhood
Chung Kyu Kim, Chui Hee Lee, Sung Hoon Cho
Clin Exp Pediatr. 1970;13(11):619-624.   Published online November 30, 1970
The thyroid disorder is not infrequently seen in the period o£ childhood. It has been a interest that why hyperthyroidism, chronic thyroiditis and thyroid tumors are frequently appear in the puberscent period, as well as somewhat poorly understood physiology of the thyroid gland in the adolescence and hypothyroidism. Authors experienced two cases of hypothyroidism, two cases of simple goiter, and a...
Case Report
A Case Report of the Protein-Losing Enteropathy
Young Joon Son, Su Hwan Su Hwan, Yong Soo Cho, Sung Hoon Cho
Clin Exp Pediatr. 1970;13(9):531-536.   Published online September 30, 1970
A case who considered to have the features of protein-losing enteropathy such as generalized edema, hypertrophy of the small bowel mucosa, hypoproteinemia, pleural effusion and ascites is reported. The study using Radioiodinated Serum Albumin demonstrated that the survival life of serum protein in patient was significantly shortened in compare to that of control group.
A Case Report of the Sturge-Weber Syndrome
Ki Yong Park, Chung Kyu Kim, Sung Hoon Cho, Chang Nak Choi
Clin Exp Pediatr. 1970;13(4):219-222.   Published online April 30, 1970
This is a case report of the Sturge-Weber Syndrome. The case was a 10-year-old girl who entered at Dept, of Pediatrics, St. Mary’s hospital in July 1969 with complaints of headache, vomiting and pain in the both lower extremities. The diagnosis was established by characteristics features of Sturge-Weber Syndrome such as portwine nevus, convulsive disorder, some degree of metal retardation...
Original Article
Clinical Observation on Chemical Pneumonitis Resulting front Poisoning of Hydrocarbon Substances in Children.
Ki Yong Park, Chui Hee Lee, Sung Hoon Cho, Jae Sung Ahn
Clin Exp Pediatr. 1970;13(3):125-130.   Published online March 31, 1970
Four cases of chemical pneumonitis in children which had been observed at St. Mary’s Hospital from Jun. 1968 to Dec. 1968, were reviewed with the following results. 1.Three cases of them were male and the rest one was female. 2.Most cases were under three years of age who were apt to swallow poisonous substances. This age incidence was related to the...
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